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Metoxia

A European Collaborative Project within Health Research, funded with the support of the Seventh Framework Programme (FP7) and coordinated by the Department of Physics, University of Oslo, Norway

Solid cancers generally contain areas with abnormally low levels of oxygen. Such areas are denoted hypoxic.

It has long been known that cancer cells in such hypoxic micro-environments are resistant to treatment.

Recent research has  shown that hypoxia in tumours is one of the major drivers of metastatic spread of cancer, the major cause of death by the disease.

Thus, hypoxia is responsible for a double effect of reducing the potential of a successful treatment of the cancer patient: Resistance to treatment and ability to spread. At the same time the very low level of oxygen found in solid tumours are specific to cancer.

Therefore, if one could develop methods that specifically located and inactivated cells in hypoxic areas one might obtain a cancer-specific effect, selective for the most harmful of the cancer cells.

This development is the core task of the METOXIA project.

 

  • Publications Oct 23, 2014 10:59 AM

    A total of 448 publications with acknowledgement to the METOXIA project, by project partners, have been listed in the EUs Participant Portal for the period 2009 - 2014. A list of the publications is now available on the website under About METOXIA-Publications.

  • Scientific developments of METOXIA Oct 21, 2014 05:01 PM

    The METOXIA project was in operation from February 2009 until July 2014. It is officially finished as an EU-funded project, nevertheless important and related research will continue with the partners of MEOXIA, and new EU-funded projects may in the future be created with partners from the METOXIA group.

    For information on the outcome of the project see METOXIA final summary of main findings and results

  • METOXIA project progress update Apr 10, 2013 03:20 PM

    A summary of the METOXIA project's progress is now available on our website under About METOXIA - Project progress . The summery is the official publishable summary as provided in our 2nd scientific report covering the period up untill 31.01.2011.

  • METOXIA%20celler1 METOXIA article in the Public Service Review Apr 10, 2013 03:20 PM

    New methods to detect cancer micro-environmental parameters are developed alongside new therapeutic principles in the form of chemicals as possible new chemotherapeutic drugs and new methods to improve radiotherapy